Nowadays, nature is something foreign to the human being. It is material that the human being uses, makes available, and exploits without scruples. But the human being is never a subject outside of space: he is always in lived and experienced relations to space, which determine and influence him. The individual is a member of a community of interdependent parts. In order to fulfil his or her life, the human being has to be able to listen to the voice of (...) nature, and abstain from the wish to control it. In such a field the lost reverence for the living world can be cultivated. Responsibility for nature is not an empty phrase, but a moral imperative that is directly connected with human life and survival. This is why we must protect the integrity of nature, and demand there be a better relationship between the human being and nature. This paper discusses the bioethical principle of 'reverence' (German Ehrfurcht ) for the living world, a concept initially presented by Albert Schweitzer using anthropological-pedagogical methods. The point of view advanced here is based on the anthropological approach of the philosopher and pedagogue O. F. Bollnow, and makes use of work by the pedagogue Yukichi Shitahodo about the anthropological preconditions of relations between a human being and the exterior world. The thesis that 'reverence' could be the basic bioethical principle governing the relationship between a human being and his environment is also founded on the modern bioethics, particularly the 'principle of responsibility' and the 'ethical imperative of prudence' as these have been formulated by philosophical biology and anthropology. (shrink)

Second harmonic generating (SHG) nanoprobes have recently emerged as versatile and durable labels suitable for in vivo imaging, circumventing many of the inherent drawbacks encountered with classical fluorescent probes. Since their nanocrystalline structure lacks a central point of symmetry, they are capable of generating second harmonic signal under intense illumination – converting two photons into one photon of half the incident wavelength – and can be detected by conventional two‐photon microscopy. Because the optical signal of SHG nanoprobes is based on (...) scattering, rather than absorption as in the case of fluorescent probes, they neither bleach nor blink, and the signal does not saturate with increasing illumination intensity. When SHG nanoprobes are used to image live tissue, the SHG signal can be detected with little background signal, and they are physiologically inert, showing excellent long‐term photostability. Because of their photophysical properties, SHG nanoprobes provide unique advantages for molecular imaging of living cells and tissues with unmatched sensitivity and temporal resolution. (shrink)

The neural representation of a repeated stimulus is the standard against which a deviant stimulus is measured in the brain, giving rise to the well-known mismatch response. It has been suggested that individuals with dyslexia have poor implicit memory for recently repeated stimuli, such as the train of standards in an oddball paradigm. Here, we examined how the neural representation of a standard emerges over repetitions, asking whether there is less sensitivity to repetition and/or less accrual of “standardness” over successive (...) repetitions in dyslexia. We recorded magnetoencephalography as adults with and without dyslexia were passively exposed to speech syllables in a roving-oddball design. We performed time-resolved multivariate decoding of the MEG sensor data to identify the neural signature of standard vs. deviant trials, independent of stimulus differences. This “multivariate mismatch” was equally robust and had a similar time course in the two groups. In both groups, standards generated by as few as two repetitions were distinct from deviants, indicating normal sensitivity to repetition in dyslexia. However, only in the control group did standards become increasingly different from deviants with repetition. These results suggest that many of the mechanisms that give rise to neural adaptation as well as mismatch responses are intact in dyslexia, with the possible exception of a putatively predictive mechanism that successively integrates recent sensory information into feedforward processing. (shrink)

Narrative persuasion, i.e. the impact of narratives on beliefs, behaviors and attitudes, and the mechanisms underpinning endorsement of conspiracy theories have both drawn substantial attention from social scientists. Yet, to date these two fields have evolved separately, and to our knowledge no study has empirically examined the impact of conspiracy narratives on real-world conspiracy beliefs. In a first study, we exposed a group of participants (n = 37) to an X-Files episode before asking them to fill in a questionnaire related (...) to their narrative experience and conspiracy beliefs. A control group (n = 41) had to answer the conspiracy beliefs items before watching the episode. Based on past findings of both the aforementioned lines of research, we hypothesized that the experimental group would show greater endorsement of conspiracy beliefs, an effect expected to be mediated by identification to the episodes’ characters. We furthermore hypothesized that identification would be associated with cognitive elaboration of the narrative information. The first two hypotheses were disproved since no narrative persuasion effect was observed. In a second study, we sought to replicate these results in a larger sample (n = 166). No persuasive effect was found in the new data and a bayesian meta-analysis of the two studies strongly supports the absence of a positive effect of exposure to narrative material on endorsement of conspiracy theories. In both studies, a significant relation between conspiracy mentality and enjoyment was observed. In the second study, this relation was fully mediated by two dimensions of perceived realism, i.e., plausibility and narrative consistency. We discuss our results, based on theoretical models of narrative persuasion and compare our studies with previous narrative persuasion studies. Implications of these results for future research are also discussed. (shrink)

The association between online Flow and Internet Gaming Disorder (IGD) has attracted significant attention. Despite the consensus that online Flow plays a pivotal role in the development of IGD and other Internet addictive behaviours, there has been a lack of consistency in measurement scales used to assess online Flow. Even widely used measures of online Flow have not been psychometrically assessed across culturally diverse populations of gamers. Such an assessment would enhance the accuracy of cross-cultural comparisons regarding the association between (...) online Flow and IGD. Attending to this need, the present study assessed the psychometric properties of the binary coded (i.e. Yes, No) Online Flow Questionnaire (OFQ), while concurrently taking into consideration country, age, language, and mode of data collection (online or face-to-face) differences. Two sequences of successive multiple group confirmatory factor analyses were used to assess the psychometric properties of the OFQ, between: a) emergent adults from the United States of America (N = 482, Mage = 25.23, SD = 2.746) and Australia (N = 168, Mage = 23.55, SD = 3.37) and b) adolescents from Greece (N = 1579, Mage = 16.12, SD =.849) and Cyprus (N = 1372, Mage = 15.54, SD =.656). Configural and partial metric invariance were confirmed between the USA and Australian samples. For the Greek and Cypriot samples, results indicated full configural and metric invariance. These results provide initial information to researchers and clinicians of the extent to which the OFQ maintains its consistency when used across cultures and invite for further cross-cultural studies in the field. Implications, as well as limitations, are discussed. (shrink)

Human-Computer Interaction (HCI) and games set a new domain in understanding people’s motivations in gaming, behavioral implications of game play, game adaptation to player preferences and needs for increased engaging experiences in the context of HCI serious games (HCI-SGs). When the latter relate with people’s health status, they can become a part of their daily life as assistive health status monitoring/enhancement systems. Co-designing HCI-SGs can be seen as a combination of art and science that involves a meticulous collaborative process. The (...) design elements in assistive HCI-SGs for Parkinson’s Disease (PD) patients, in particular, are explored in the present work. Within this context, the Game-Based Learning (GBL) design framework is adopted here and its main game-design parameters are explored for the Exergames, Dietarygames, Emotional games, Handwriting games, and Voice games design, drawn from the PD-related i-PROGNOSIS Personalized Game Suite (PGS) (www.i-prognosis.eu) holistic approach. Two main data sources were involved in the study. In particular, the first one includes qualitative data from semi-structured interviews, involving 10 PD patients and four clinicians in the co-creation process of the game design, whereas the second one relates with data from an online questionnaire addressed by 104 participants spanning the whole related spectrum, i.e., PD patients, physicians, software/game developers. Linear regression analysis was employed to identify an adapted GBL framework with the most significant game-design parameters, which efficiently predict the transferability of the PGS beneficial effect to real-life, addressing functional PD symptoms. The findings of this work can assist HCI-SG designers for designing PD-related HCI-SGs, as the most significant game-design factors were identified, in terms of adding value to the role of HCI-SGs in increasing PD patients’ quality of life, optimizing the interaction with personalized HCI-SGs and, hence, fostering a collaborative human-computer symbiosis. (shrink)

Wittgenstein’s concepts shed light on the phenomenon of schizophrenia in at least three different ways: with a view to empathy, scientific explanation, or philosophical clarification. I consider two different “positive” wittgensteinian accounts―Campbell’s idea that delusions involve a mechanism of which different framework propositions are parts, Sass’ proposal that the schizophrenic patient can be described as a solipsist, and a Rhodes’ and Gipp’s account, where epistemic aspects of schizophrenia are explained as failures in the ordinary background of certainties. I argue that (...) none of them amounts to empathic-phenomenological understanding, but they provide examples of how philosophical concepts can contribute to scientific explanation, and to philosophical clarification respectively. (shrink)

When individuals cannot make up their mind, they sometimes use a random decision-making aid such as a coin to make a decision. This aid may also elicit affective reactions: A person flipping a coin may (dis)like the outcome, and thus decide according to this feeling. We refer to this process as catalysing decisions and to the aid as catalyst. We investigate whether using a catalyst may not only elicit affect but also result in more affect-based decision making. We used different (...) online studies that examine affect-driven decisions by investigating scope insensitivity (indirect behavioural measure) and self-reported weight given to feelings versus reasons in hypothetical donation decisions. Study 1a showed that a catalyst (a lottery wheel) lead to more scope insensitive (i.e. affect-driven) donations. Study 1b included several changes and did not replicate these results. Study 2 (preregistered) examined scope insensitivity but did not replicate previous results; Study 3 (preregistered) looked at the weight given to feelings versus reason. Although catalyst (compared to control) participants descriptively reported relying more on feelings, this difference did not reach significance. In contrast to lay beliefs, results do not indicate support for the hypothesis that using a catalyst results in more affect-based hypothetical donation decisions. (shrink)

_This is a personal account based on many years experience as a medical writer. It considers aspects of medical writing with particular focus on the intellectual and ethical dilemmas it can raise. What makes medical writing both so interesting and so challenging is the fact that it often takes place at the border between different disciplines. For example, it straddles both science and art. Ethical issues also arise at the boundaries between academia and commerce. Until recently there have been few (...) guidelines to help navigate such potentially dangerous territory. I have been privileged to be involved in developing two such guidelines and I describe how I hope the Good Publication Practice guidelines for pharmaceutical companies and the European Medical Writers Association guidelines may improve the practice of this fascinating profession, Medical Writing._. (shrink)

The vexed question of the exact significance of the name of Mavortius in the old Putean MS. of Prudentius has again been called into court in the recent discussions of the Mavortian recension of Horace, and is fully treated in Dr. Bick's Horazkritik seit 1880, pp. 31–35. As Dr. Bick has done me the honour of subjecting my former articles on the question to his criticism, I feel called upon to say something in defence of the view I maintained. I (...) willingly grant him that perhaps I laid too strong a stress on the connection of the question with Horatian criticism; but I do so, I fear, not as a convert to his arguments in favour of the view that Put. is merely a copy of a MS. that had Mavortius' autograph written in it, and that therefore that name is part of a lost subscriptio, but precisely for the contrary reason, that I consider I was too much influenced by former advocates of that view. That there is no ground for assuming the name to be part of a lost subscriptio I am more than ever convinced, and my object here is to endeavour to show that the whole argument based on a false premise. (shrink)

I venture to call the attention of classical scholars to two legends about Roman Emperors gleaned amid the arid waste of theological nonsense which passed for literature among the Copts, in the hope that they may have better luck than I have had in tracing them to some classical source. The first is taken from MS. Par. Copte 131, fol. 40, a single leaf of what seems to be a geographical and historical encyclopaedia.1 The writer who is treating in a (...) very discursive way of Ethiopia, states that Nero or Domitian—a strange pair to run in double harness—caused an island in the Red Sea to be watered with oil. The description of that island is mixed up with a mention of the original divisions of the Indians—a term which as usual in early days embraces both Indians and Ethiopians,—and their subsequent changes; and as that too may be of interest to students of ancient geography, I will translate the passage in full. (shrink)

In this paper I report a public discussion with E.P. Wigner that took place in 1987 at a conference on fundamental problems in Quantum Mechanics. In it Wigner clarified an idea that was widely attributed to him about consciousness playing a direct role in the quantum measurement process. He significantly revised that idea, and distanced himself from the earlier notion that consciousness plays a direct role.

Ongevraagde ouverture, door F. O. van Gennep.--Ethiek als waagstuk, door F. van Raalten.--Het juridisch aspect van de rabbijnse ethiek, door M. A. Beek.--Is er een eigen christelijke ethiek? Door H. J. Heering.--Het radicalisme in de ethiek, door F. O van Gennep.--Ethiek en praktijk van de geweldloosheid van Dr. Martin Luther King, door J. W. Schulte Nordholt.--Politiek pastoraat, door K. Strijd.--Mythe en ethiek, door F. van Raalten.--Veritas poetica, door C. W. Mönnich.--Ethiek in de counseling, door H. R. Wijngaarden.--Bibliografische gegevens uit het (...) werk van Prof. Dr. E. L. Smelik (p. 141-142). (shrink)

As a field, ethics is driven by the desire to help guide human life and human activities. Yet, what are the standards or guideposts indicating that a given policy or practice change actually contributes meaningfully to such desires and aspirations? In other words, how do we know if we have achieved meaningful ethical outcomes and enactment processes? Unfortunately, there are many examples of ethically oriented actions that were well intentioned but carried out in a way that undermined some of the (...) values they intended on promoting or led to unexpected undesirable outcomes. In this paper, building on an account of ethics as a pragmatist pursuit of deliberative wisdom, I identify and discuss four procedural guideposts which can help evaluate if a process of inquiry is an ethical one oriented toward human flourishing. First, situational awareness and continuity designates the need to keep in sight the nature of the situation at stake to ensure that the enactment process does not derail from a cardinal human flourishing orientation. Second, a meaningful ethical enactment should distribute opportunities for participation such that it is not only one’s autonomy (e.g., the ethicist) that is developed and exercised but that positive relationships are also fostered through the growth of others. Third, enactments must strive for more than simple avoidance of encroachment of wrongs but aim for the promotion of praiseworthy practices that pursue what is envisioned as being the better and most compelling vision. Fourth, an ethics process should be conducive of personal growth and mutual learning. (shrink)

Linguistic study of Mongolian traditional classical translation.

Kvantory kak vtoropori︠a︡dkovye predikaty: ot Frege k abstraktnym logikam -- Kvantory kak funkt︠s︡ii vybora: ot Pirsa k IF-logikam -- Kvantifikat︠s︡ii︠a︡ i ėkzistent︠s︡ii︠a︡ -- Ėkzistent︠s︡ii︠a︡ i negat︠s︡ii︠a︡.

'Jousse - il a trouvé un filon, comme on dit', confie Bergson dans un entretien avec Lydie Adolphe. La relation que Marcel Jousse, chercheur, professeur, homme d'Église, entretient tout au long de ses quelque quarante ans d'enseignement avec le philosophe Henri Bergson est pour le moins paradoxale. Entre admiration et rejet, Jousse revendique 'sa' lecture de Bergson. Libre et inspirante, souvent critique, voire frôlant la caricature, cette lecture tonique agit en retour sur le lecteur, qu'il soit connaisseur de l'œuvre de (...) Bergson ou pas. Selon Jousse, le geste corporel-manuel, le geste global, est au cœur de la pensée du philosophe. Bergson joue sa pensée avec ses mains, avec tout son corps avant de la jeter dans ses livres. La connaissance des lois anthropologiques du Style oral formulées par Jousse permet de mieux saisir la particularité du style de Bergson, proche de celui de Péguy, et qui s'apparente au style oral des rythmo-mimeurs. Jousse, Bergson : deux noms qui ont marqué leur époque. Le lien fort qui unit les deux penseurs est au cœur de cette enquête - que l'on pourrait aussi écrire 'en quête' - à la fois philosophique et historique. Ce livre s'inscrit dans la longue liste des 'lecteurs de Bergson' qu'ils soient ou non bergsoniens."--Page 4 of cover. (shrink)

Ralph Waldo Emerson said, “a Foolish consistency is the hobgoblin of little minds, adored by little statesmen and philosophers and divines.” The alleged evidence has mounted that ordinary folk are prone to inconsistency, and particularly that they are prone to inconsistency when it comes to probabilistic judgments. I write “alleged,” because it is open to question whether the experiments that provide this evidence are well designed—in particular whether Quine’s principle of logistical charity has been followed. I also do so because (...) in some cases of probability judgments the untutored intuitions of ordinary people seem to be at least as good as, and perhaps better than, the intuitions of those who run the experiments. (shrink)